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Generic Premarin is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., vaginal dryness).
Before using
Warning: conjugated estrogens have been reported to increase the chance of womb (endometrial) cancer in women who have been through menopause, especially in women with a uterus who receive estrogen-only hormone therapy. Estrogens may also increase the risk of cancer of the ovary/breast. Estrogen-containing medicines should not be used to prevent heart disease. Estrogen given in combination with another hormone (progestin) for replacement therapy can infrequently cause heart disease (e.g., heart attacks), stroke, serious blood clots, and cancer of the breast. These risks appear to depend on the length of time this medicine is used and the amount of estrogen per dose. Therefore, this medicine should be used for the shortest possible length of time at the lowest effective dose, so you obtain the benefits and minimize the chance of serious side effects from long-term treatment.
If you use
Generic Premarin for an extended period, you should be evaluated at least once yearly (see cautions section). This medicine is not effective in preventing/treating a tendency toward miscarriages nor the threat of miscarriage. This medicine must not be used during pregnancy because its use may result in birth defects or cancer later in the child's life (see cautions section).
Additional monitoring of your dose or condition may be needed if you are using other vaginal medicines. Do not start or stop any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including a family medical history (e.g., especially breast lumps/cancer), asthma, diabetes, seizures, migraine headaches, liver or kidney disease, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy, yellowing of eyes/skin during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids/endometriosis), cholesterol/lipid problems, gallbladder disease, excessive weight gain, certain blood disorder (porphyria), allergies, pregnancy, or breast-feeding.
Use of this medicine is not recommended if you have certain medical conditions including undiagnosed abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially non-metastatic type), blood clots, or active/recent stroke or heart attack. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Directions
Follow the directions for using
Generic Premarin provided by your doctor. This medicine comes with a patient leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. Fill the applicator with the medicine according to the directions. Insert the applicator high into the vagina and press the plunger to release the medicine. Clean the applicator with warm soapy water and rinse well. Do not boil or use hot water to clean the applicator. Follow your dosing schedule closely. It is best to schedule each dose about the same time of the day.
Store this medicine at room temperature 77 degrees f (25 degrees c), away from heat, moisture, and light. If you miss a dose of this medicine, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
IMPORTANT NOTICE
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider.
